The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

This editorial introduces the Journal of Consciousness Studies special issue on "Animal Consciousness". The 15 contributors and co-editors answer the question "How should we study animal consciousness scientifically?" in 500 words or fewer.

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

Background and aims: Recent investigations have highlighted the value of neuropsychological testing for the assessment and screening of Alcohol-Related Brain Damage. The aim of the present study was to evaluate the suitability of the Addenbrooke’s Cognitive Examination and the Repeatable Battery for the Assessment of Neuropsychological Status for this purpose. Methods: Comparing 28 participants with ARBD and 30 alcohol-dependent participants without ARBD we calculated Area Under the Curve statistics, sensitivity and specificity values, base-rate adjusted predictive values, and likelihood ratios for (...) both tests. Results: High levels of screening accuracy were found for the total scores of both the ACE-III and RBANS at multiple cut-off points. Removing participants with a history of polysubstance from the samples improved the diagnostic capabilities of the RBANS substantially, while only minor improvements to the ACE-III’s accuracy were observed. Conclusions: Overall, both the ACE-III and RBANS are suitable tools for ARBD screening within an alcohol-dependent population, though the RBANS is the superior of the two. Clinicians using these tools for ARBD screening should be cautious of false-positive outcomes and should therefore combine them with other assessment methods and more detailed neuropsychological testing before reaching diagnostic decisions. (shrink)

For Plato and Aristotle, arete (traditionally translated as "virtue") was the essential object of human admiration and striving, and even the key to happiness. Their work continues to inspire reflection on fundamental questions of ethics and politics today, as the fourteen new essays collected here demonstrate. -/- Contributors: Lidia Palumbo, Eva Anagnostou-Laoutides, Ryan M. Brown, Jay R. Elliott, Guilherme Domingues da Motta, Federico Casella, Jonathan A. Buttaci, George Harvey, Mark Ralkowski, Gary S. Beck, Paula Gottlieb, Giulio di Basilio, (...) Audrey L. Anton, and Elena Bartolini. (shrink)

Numerous social, economic and academic pressures can have a negative impact on representations of biomedical research. We review several of the forces playing an increasingly pernicious role in how health and science information is interpreted, shared and used, drawing discussions towards the role of narrative. In turn, we explore how aspects of narrative are used in different social contexts and communication environments, and present creative responses that may help counter the negative trends. As traditional methods of communication have in many (...) ways failed the public, changes in approach are required, including the creative use of narratives. (shrink)

Moral injury results from the violation of deeply held moral commitments leading to emotional and existential distress. The phenomenon was initially described by psychologists and psychiatrists associated with the US Departments of Defense and Veterans Affairs but has since been applied more broadly. Although its application to healthcare preceded COVID-19, healthcare professionals have taken greater interest in moral injury since the pandemic’s advent. They have much to learn from combat veterans, who have substantial experience in identifying and addressing moral injury—particularly (...) its social dimensions. Veterans recognise that complex social factors lead to moral injury, and therefore a community approach is necessary for healing. We argue that similar attention must be given in healthcare, where a team-oriented and multidimensional approach is essential both for ameliorating the suffering faced by health professionals and for addressing the underlying causes that give rise to moral injury. (shrink)

Task unrelated thought (TUT) refers to thought directed away from the current situation, for example a daydream. Three experiments were conducted on healthy participants, with two broad aims. First, to contrast distributed and encapsulated views of cognition by comparing the encoding of categorical and random lists of words (Experiments One and Two). Second, to examine the consequences of experiencing TUT during study on the subsequent retrieval of information (Experiments One, Two, and Three). Experiments One and Two demonstrated lower levels of (...) TUT and higher levels of word-fragment completion whilst encoding categorical relative to random stimuli, supporting the role of a distributed resource in the maintenance of TUT. In addition the results of all three experiments suggested that experiencing TUT during study had a measurable effect on subsequent retrieval. TUT was associated with increased frequency of false alarms at retrieval (Experiment One). In the subsequent experiments TUT was associated with no advantage to retrieval based on recollection, by manipulating instructions at encoding (Experiment Two), and/or at retrieval (Experiment Three). The implications of the results of all three experiments are discussed in terms of recent accounts of memory retrieval and conscious awareness. (shrink)

Despite legislation and public education, racism and sexism are alive and well. Though pre‐conceptive gender selection may enhance procreative liberty, this technology presents two disturbing questions. First, does sex selection represent underlying parental sexism? Second, by performing gender selection, do medical professionals perpetuate sexism? It will be maintained that pre‐conceptive sex selection is sexist as it reflects parental anticipation of stereotypical gender based behavior. Perhaps even more incriminating, sex selection forces parents to prefer one sex over another, to place a (...) value on gender. This emphasis on sex conflicts with societal goals which urge, and often legally require, individuals to ignore gender. We will assert that pre‐conceptive gender selection exemplifies sexism in its purest most blatant form as prior to conception, before parents can possibly know anything about their child, gender dominates the calculus of a child’s worth. We will also emphasize that physicians, by facilitating sex selection, legitimize the motivations of their patients and provide de facto support of sexism. In a similar vein, arguments against pre‐conceptive race selection will be made. (shrink)

The modern university is a demoralizing institution, largely devoted to the propagation of nihilism and liberation of desire. The apotheosis of this hungry god of the untrammeled will has taken more than 200 years, but the slow ascent has given humanistic scholarship its basic shape. The ascent of 'reason' over tradition and religion, at the end of the eighteenth century, caused conservative thought to emerge, reluctantly, and frame rational defenses of natural (i.e. spontaneously evolved) social institutions and belief systems. This (...) has always been handicapped by the need to fight rationalism with reason. This same ascent inspired revolutionary theorists to frame their ringing denunciations and inspiring panaceas, most of which proved purely destructive because of the tragic inability of revolutionary practice to produce the promised and indispensable metanoia. Partly due to the limited success of conservative thought and revolutionary theory, untrammeled will has, more recently, ascended over reason, tradition, and religion, to give us the postmodern nihilism of Luciferian scholars. (shrink)

There is more to modern health than new scientific discoveries, the development of new technologies, or emerging or re‐emerging diseases. World events and experiences, such as the AIDS epidemic and the humanitarian emergencies in Bosnia and Rwanda, have made this evident by creating new relationships among medicine, public health, ethics, and human rights. Each domain has seeped into the other, making allies of public health and human rights, pressing the need for an ethics of public health, and revealing the rights‐related (...) responsibilities of physicians and other health care workers. (shrink)

The COVID-19 pandemic has been unprecedented, in every sense of the word. At the time of writing, there have been nearly 80 million confirmed cases of coronavirus and nearly 2 million deaths worldw...

This article examines the philosophical methodology of intuitions beginning with an argument developed by Max Deutsch and Herman Cappelen over the descriptive adequacy of what Cappelen calls “methodological rationalism”, and their own preferred view, “intuition nihilism”. Based on inadequacies in both accounts, it offers a descriptive take on intuition-deploying philosophical practice today via what it calls “Protean Crypto-Rationalism”. It then describes the epistemic profile of the appeal to intuition, listing four key aspects of the basic shape of intuition-deploying philosophical practice: (...) primacy of cases, flexibility of report format, freedom of stipulation, and interpretation-hungry. It also considers several sources of error for intuitions featured in at least the informal methodological lore of philosophy, namely: misconstruals, modal confusions, pragmatics/semantics confusion, and “tin ear”. Finally, it explores the problem of methodological ignorance and inferential demand, particularly the typical practices of philosophical inference that operate on the premises delivered by appeal to intuitions. (shrink)

In this paper we propose to argue for two claims. The first is that a sizeable group of epistemological projects – a group which includes much of what has been done in epistemology in the analytic tradition – would be seriously undermined if one or more of a cluster of empirical hypotheses about epistemic intuitions turns out to be true. The basis for this claim will be set out in Section 2. The second claim is that, while the jury is (...) still out, there is now a substantial body of evidence suggesting that some of those empirical hypotheses are true. Much of this evidence derives from an ongoing series of experimental studies of epistemic intuitions that we have been conducting. A preliminary report on these studies will be presented in Section 3. In light of these studies, we think it is incumbent on those who pursue the epistemological projects in question to either explain why the truth of the hypotheses does not undermine their projects, or to say why, in light of the evidence we will present, they nonetheless assume that the hypotheses are false. In Section 4, which is devoted to Objections and Replies, we’ll consider some of the ways in which defenders of the projects we are criticizing might reply to our challenge. Our goal, in all of this, is not to offer a conclusive argument demonstrating that the epistemological projects we will be criticizing are untenable. Rather, our aim is to shift the burden of argument. (shrink)

Malacologists took notice of tree snails in the genus Liguus during the last decades of the nineteenth century. Since then, Liguus have undergone repeated shifts in identity as members of species, states, shell collections, backyard gardens, and engineered wildernesses. To understand what Liguus are, this paper examines snail enthusiasts, collectors, researchers, and conservationists—collectively self-identified as Liggers—in their varied landscapes. I argue that Liguus, both in the scientific imaginary and in the material landscape, mediated knowledge-making processes that circulated among amateur and (...) professional malacologists across the United States and Cuba during the twentieth century. Beginning with an examination of early Liggers’ work in Florida and Cuba, this paper demonstrates how notions of taxonomy and biogeography informed later efforts to understand Liguus hybridization and conservation. A heterogeneous community of Liggers has had varied and at times contradictory commitments informed by shifting physical, social, and scientific landscapes. Genealogizing those commitments illuminates the factors underpinning a decision to undertake the until now little-chronicled large-scale and sustained transplantation of every living Floridian form of Liguus fasciatus into Everglades National Park. The social history of Liggers and Liguus fundamentally blurs distinctions between professional scientists and amateur naturalists. The experiences of a diverse cast of Liggers and their Liguus snails historicize the complex character of human-animal relations and speak to the increasing endangerment of many similarly range-restricted invertebrates. (shrink)

The larger philosophical world has on the whole turned from a mix of averted gaze and outright antipathy toward x‐phi, to a mix of grudging acceptance and enthusiastic embrace. This chapter explains that the experimental philosophy is relevant, and that it is dangerous, and explains some ways that people can do more to remain both. Experimental philosophy's semi‐official sigil of the burning armchair has advertised its dangerousness for the past decade and a half as well. The chapter explains that it (...) is a threat that is every bit as potently present in positive program x‐phi as it is in negative program work. To explore the idea that experimental philosophy's positive contributions will still be primarily negative in nature, the chapter interrogates the passage from Timothy Williamson. It focuses on the wheat‐from‐chaff project of separating signal from noise in the evidence produced by intuitions and the like. (shrink)

Next SectionIn an online study conducted separately in the UK and the US, participants rated the acceptability and fairness of four interventions: two types of financial incentives and two types of medical interventions. These were stated to be equally effective in improving outcomes in five contexts: weight loss and smoking cessation programmes, and adherence in treatment programmes for drug addiction, serious mental illness and physiotherapy after surgery. Financial incentives were judged less acceptable and to be less fair than medical interventions (...) across all five contexts. Context moderated the relative preference between rewards and penalties: participants from both countries favoured rewards over penalties in weight loss and treatment for serious mental illness. Only among US participants was this relative preference moderated by perceived responsibility of the target group. Overall, participants supported funding more strongly for interventions when they judged members of the target group to be less responsible for their condition, and vice versa. These results reveal a striking similarity in negative attitudes towards the use of financial incentives, rewards as well as penalties, in improving outcomes across a range of contexts, in the UK and the USA. The basis for such negative attitudes awaits further study. (shrink)

Griffiths and Machery contend that the concept of innateness should be dispensed with in the sciences. We contend that, once that concept is properly understood as what we have called 'closed process invariance', it is still of significant use in the sciences, especially cognitive science.

Rowan Williams has consistently given expression to Christian faith in surprising and genera-tive ways, especially through the language of ‘excess’ and through contemplating the excess in the narrative and identity of Christ. By attending to the grammar of excess, this essay draws out elements of the metaphysics of holiness in dialogue with Williams. I ask how creaturely being can be sustained by the holiness which generates all things without leaving holiness so ubiq-uitous as to be either trivial or hidden. I (...) respond to this problem by arguing that holy lives and communities make visible the ontological dependence of all things on God. Finally, this pro-vides a way of recognizing the value of the metaphysical imagination in the pursuit of holiness. (shrink)

Experimental philosophy is often regarded as a category mistake. Even those who reject that view typically see it as irrelevant to standard philosophical projects. We argue that neither of these claims can be sustained and illustrate our view with a sketch of the rich interconnections with philosophy of science.Keywords: Science; Philosophy; Experimental Philosophy.

How ought we to go about forming and revising our beliefs, arguing and debating our reasons, and investigating our world? If those questions constitute normative epistemology, then I am interested here in normative metaepistemology: the investigation into how we ought to go about forming and revising our beliefs about how we ought to go about forming and revising our beliefs -- how we ought to argue about how we ought to argue. Such investigations have become urgent of late, for the (...) methodology of epistemology has reached something of a crisis. For analytic epistemology of the last half-century has relied overwhelmingly on intuitions,1 and a growing set of arguments and data has begun to call this reliance on intuition seriously into question (e.g., Weinberg, Nichols, and Stich 2001; Nichols, Stich, and Weinberg 2003; Cummins 1998). Although that method has not been entirely without defenders (BonJour 1998; Bealer 1996; Jackson 1998; Sosa forthcoming; Weatherson 2003), these defenses have not generally risen to the specific challenges leveled by the anti-intuitionist critics. In particular, the critics have attacked specific ways of deploying intuitions, and the defenders have overwhelmingly responded with in-principle defenses of the cogency of appealing to intuition. An analogy here would be someone’s responding to arguments alleging systematic.. (shrink)

The ABCs of Education is a philosophy of education introducing a unique learning perspective that promotes interest based learning for the purpose of fostering authentic empowerment via civic engagement. This book begins by clarifying the function of education and the need for creating safe and welcoming learning environments by modeling altruistic practices. Altruism is justified with a that a theory that explains synergy in the context of education. The book then goes on to introduce a concept referred to as Biosintegrumology. (...) This is book is the most comprehensive introduction of Biosintegumology to date. Biosintegrumology is used to demonstrate the importance of student interest in curriculum design. Finally, the book concludes with detailing the role of civics in education. (shrink)

This is the first issue of a new journal formed by the merger of Ethics, Place and Environment and Philosophy and Geography. We trust that you will find that this new journal continues to advance a...

(2003). No community without spectacle: A comment on Olwig's Landscape, Nature, and the Body Politic. Philosophy & Geography: Vol. 6, No. 2, pp. 263-265. doi: 10.1080/1090377032000114705.

In his Experiments in Ethics, Appiah focuses mostly on the dimension of naturalism as a naturalism of deprivation - naturalism’s apparent robbing us of aspects of the world that we had held dear. The aim of this paper is to remind him of that naturalism has a dimension of plenitude as well - its capacity to enrich our conception of the world as well. With regard to character, we argue that scientific psychology can help provide a conception of character as (...) dynamic, in a way that may preserve many key aspects of eudaimonistic ethics from the situationists’ challenge. With regard to intuition, we address Appiah’s worry that naturalistic explanations of the sources of our intuitions may leave us feeling that those intuitions have been thereby debunked. We suggest that it may be that feeling of debunking that should itself be debunked. (shrink)

Recent experimental philosophy arguments have raised trouble for philosophers' reliance on armchair intuitions. One popular line of response has been the expertise defense: philosophers are highly-trained experts, whereas the subjects in the experimental philosophy studies have generally been ordinary undergraduates, and so there's no reason to think philosophers will make the same mistakes. But this deploys a substantive empirical claim, that philosophers' training indeed inculcates sufficient protection from such mistakes. We canvass the psychological literature on expertise, which indicates that people (...) are not generally very good at reckoning who will develop expertise under what circumstances. We consider three promising hypotheses concerning what philosophical expertise might consist in: (i) better conceptual schemata; (ii) mastery of entrenched theories; and (iii) general practical know-how with the entertaining of hypotheticals. On inspection, none seem to provide us with good reason to endorse this key empirical premise of the expertise defense. (shrink)

In many ways, Maddie’s case brings together some of the most challenging features seen in clinical ethics consultation. First, it centers around a heart-wrenching event—the near-drowning of a young...

Using empirical evidence to attack intuitions can be epistemically dangerous, because various of the complaints that one might raise against them (e.g., that they are fallible; that we possess no non-circular defense of their reliability) can be raised just as easily against perception itself. But the opponents of intuition wish to challenge intuitions without at the same time challenging the rest of our epistemic apparatus. How might this be done? Let us use the term “hopefulness” to refer to the extent (...) to which we possess a good capacity for the detection and correction of the errors of any fallible source of evidence. I argue that we should not trust putative sources of evidence that are substantially lacking in hopefulness (even if they are basically reliable), and that we are indeed already operating under such a norm in our ordinary and scientific practices. I argue further that the philosophical practice of the appeal to intuitions is, in these terms, badly hopeless... (shrink)

The simple principle of individual liberty evidently does identify particular rights as rights which ought to be recognised and enforced by the laws and customs of every civil society, namely, the rights of self-regarding liberty and individuality. If sex between consenting adults is purely self-regarding conduct under some conditions, for instance, then adults should have a right to spontaneously engage in sex under those conditions if they wish.

Standard philosophical methodology which proceeds by appeal to intuitions accessible "from the armchair" has come under criticism on the basis of empirical work indicating unanticipated variability of such intuitions. Loose constitutivity---the idea that intuitions are partly, but not strictly, constitutive of the concepts that appear in them---offers an interesting line of response to this empirical challenge. On a loose constitutivist view, it is unlikely that our intuitions are incorrect across the board, since they partly fix the facts in question. But (...) we argue that this ratification of intuitions is at best rough and generic, and can only do the required methodological work if it operates in conjunction with some sort of further criteria of theory selection. We consider two that we find in the literature: naturalness (Brian Weatherson, borrowing from Lewis) and charity (Henry Jackman, borrowing from Davidson). At the end of the day, neither provides the armchair philosopher complete shelter from extra-armchair inquiry. (shrink)

While Taylor and Habermas respectively follow communitarian vs cosmopolitan lines in their political theories, trends in each of their writings on religion in a global context have taken surprising turns toward convergence. However, what both views lack would be a further analytical and normative classification that better captures the pluralistic dimensions of this shared turn. I consider Taylor’s critique of Habermas’ appeals to constitutional patriotism that lead to recanting the exceptionalist thesis attributed to the USA in order to own up (...) to the exceptionalism of European secularity. I then take up the more pragmatic concern of the religion in a global public, using their writings on Islam in the USA and in the EU as a litmus test for the epistemic scope of our respective degrees of Jamesian openness, referring to the inherent potentials for the moral, social and political integration of immigrants and minorities into a more encompassing cosmoi politanism. (shrink)

This article sketches a theory of time-binding communication, which is to say communication that unifies widely separated times much as space-binding communication unifies widely separated places. Drawing from the work of Harold Innis, it first describes the function and character of time-binding communication as a means to social continuity. Then, following Alasdair MacIntyre and Michael Oakshott, it explains the nature and necessary circumstances of this sort of time-binding communication, or tradition. It discusses the character, consequences, and causes of decadence - (...) radical discontinuity - as these have been described by Richard Weaver, C. E. M. Joad, and Jacques Barzun. Finally, it turns to David Lowenthal's notion of the past as a 'foreign country' in an effort to explain the relations between modernity and both tradition and decadence, as well as the geography of tradition and decadence in the modern world. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:A New Essenism: Heinrich Graetz and MysticismJonathan M. ElukinSince the Reformation, European Christians have sought to understand the origins of Christianity by studying the world of Second Temple Judaism. These efforts created a fund of scholarly knowledge of ancient Judaism, but they labored under deep-seated pre judices about the nature of Judaism. When Jewish scholars in nineteenth-century Europe, primarily in Germany, came to study their own history as part (...) of the Wissenschaft des Judentums movement, they too looked to the ancient Jewish past as a crucia l element in understanding Jewish history.A central figure in the Wissenschaft movement was Heinrich Graetz (1817–1891). 1 In his massive history of the Jews, the dominant synthesis of Jewish history until well into the twentieth century, Graetz constructed a narrative of Jewish history that imbedded mysticism deep within the Jewish past, finding its origins in the first-cen tury sectarian Essenes. 2 Anchoring mysticism among the Essenes was crucial for Graetz’s larger narrative of the history of Judaism, which he saw as a continuing struggle between the corrosive effects of mysticism [End Page 135] and the rational rabbinic tradition. An unchanging mysticism was a mirror image of the unchanging monotheistic essence of normative Judaism that dominated Graetz’s understanding of Jewish history. Ironically, this narrative model of the history of mystic ism may have been influenced by Christian attacks on Judaism itself, a point which I can briefly take up at the conclusion of the article. First let us turn to the role that the Essenes played in Graetz’s historical ideology of mysticism.Graetz inherited a long intellectual tradition about the identity of first-century sectarians. Ever since the fourth-century historian Eusebius asserted that the therapeutae, a group mentioned by Philo, were actually Christian monks, the religious identity of these Alexandrian sectarians—distinct from the Essenes—had been the subject of constant debate. 3 Were they Jews or Christian ascetics? During the Middle Ages the tradition articulated by Eusebius gave the Church an additional claim for the antiquity of one of its central institutions. The religious identity of the Essenes, a seemingly similar sectar ian group mentioned by Josephus and other ancient historians, also became a point of dispute. 4 The secluded, monastic life of the Essenes made them equally likely candidates to be proto-Christians. The dispute over the alleged Christian nature of the therapeutae and the Essenes would survive, after generations of Catholic and Protestant sch olarly polemic, into nineteenth-century scholarship on late antique Judaism. 5It was in the work of Graetz that the Essenes and their putative relationship to Christianity received the fullest treatment by a Jewish historian. 6 Since the only documented therapeutae were in Alexandria, they could not be considered [End Page 136] likely sources—even if they were Jewish—for a nascent Palestinian Christianity. The Essenes offered more fertile ground to explore the relationship between Judaism and early Christianity.Graetz’s argument that Jesus and Christianity had their origins among the Essenes developed in the context of a fierce scholarly polemic between Christians and Jews in the nineteenth century as well as in the context of internal Jewish debates. Before exp loring this larger background, let us first see how Graetz made his case for the connection between Jesus and the Essenes. Making this connection was crucial for Graetz if Christianity was to be understood as the first systematic expression of a mysticism that had flourished among the Essenes.The Essenes were the first, according to Graetz, to articulate a firmly held belief in the coming of the Messiah, a belief which had grown in intensity during the turmoil and oppression of Roman rule. 7 Christianity, “or rather this Essenism intermingled with foreign elements,” had its origins in this messianic longing. 8 It was no surprise that John the Baptist was the first to proclaim the arrival of the Messiah, since he was so obviously an Essene. 9 Graetz makes his case for John’s Essene background on the apparent similarity of their habits, most notably the common theme of daily immersion and the fact that both John the Baptist (“oder richtiger der Essäer” [“or rather... (shrink)

New methods of marking cells enable single clones to be followed during embryonic development. They can be used for the construction of fate maps and for the investigation of induction and determination.

It has become increasingly popular to respond to experimental philosophy by suggesting that experimental philosophers haven’t been studying the right kind of thing. One version of this kind of response, which we call the reflection defense, involves suggesting both that philosophers are interested only in intuitions that are the product of careful reflection on the details of hypothetical cases and the key concepts involved in those cases, and that these kinds of philosophical intuitions haven’t yet been adequately studied by experimental (...) philosophers. Of course, as a defensivemove, thisworks only if reflective intuitions are immune from the kinds of problematic effects that form the basis of recent experimental challenges to philosophy’s intuition-deploying practices. If they are not immune to these kinds of effects, then the fact that experimental philosophers have not had the right kind of thing in their sights would provide little comfort to folks invested in philosophy’s intuition-deploying practices. Here we provide reasons to worry that even reflective intuitions can display sensitivity to the same kinds of problematic effects, although possibly in slightly different ways. As it turns out, being reflective might sometimes just mean being wrong in a different way. (shrink)